Transcription Factor SOX5 Promotes the Migration and Invasion of Fibroblast-Like Synoviocytes in Part by Regulating MMP-9 Expression in Collagen-Induced Arthritis

OBJECTIVES: Fibroblast-like synoviocytes (FLS) exhibit a unique aggressive phenotype in rheumatoid arthritis (RA). Increased FLS migration and subsequent invasion of the extracellular matrix are essential to joint destruction in RA. Our previous research reported that transcription factor SOX5 was h...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shi, Yumeng, Wu, Qin, Xuan, Wenhua, Feng, Xiaoke, Wang, Fang, Tsao, Betty P., Zhang, Miaojia, Tan, Wenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906798/
https://ncbi.nlm.nih.gov/pubmed/29706965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00749
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