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Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

DEP domain containing mTOR-interacting protein (DEPTOR) was originally identified as an in vivo dual inhibitor of mechanistic target of rapamycin (mTOR). It was recently reported to be involved in renal physiology and pathology in vitro; however, its detailed roles and mechanisms in vivo are complet...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Caixia, Dai, Huaiqian, Xiong, Zhi, Song, Qiancheng, Zou, Zhipeng, Li, Mangmang, Nie, Jing, Bai, Xiaochun, Chen, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906659/
https://ncbi.nlm.nih.gov/pubmed/29670094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0483-3
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