Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury

Peroxisome proliferator-activated receptor-α (PPARα) activation attenuates cisplatin (CP)-mediated acute kidney injury by increasing fatty acid oxidation, but mechanisms leading to reduced renal triglyceride (TG) accumulation could also contribute. Here, we investigated the effects of PPARα and CP o...

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Main Authors: Li, Shenyang, Nagothu, Kiran, Ranganathan, Gouri, Ali, Syed M., Shank, Brian, Gokden, Neriman, Ayyadevara, Srinivas, Megyesi, Judit, Olivecrona, Gunilla, Chugh, Sumant S., Kersten, Sander, Portilla, Didier
格式: Artigo
語言:Inglês
出版: American Physiological Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433869/
https://ncbi.nlm.nih.gov/pubmed/22622461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00111.2012
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