Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury

Peroxisome proliferator-activated receptor-α (PPARα) activation attenuates cisplatin (CP)-mediated acute kidney injury by increasing fatty acid oxidation, but mechanisms leading to reduced renal triglyceride (TG) accumulation could also contribute. Here, we investigated the effects of PPARα and CP o...

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Autors principals: Li, Shenyang, Nagothu, Kiran, Ranganathan, Gouri, Ali, Syed M., Shank, Brian, Gokden, Neriman, Ayyadevara, Srinivas, Megyesi, Judit, Olivecrona, Gunilla, Chugh, Sumant S., Kersten, Sander, Portilla, Didier
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433869/
https://ncbi.nlm.nih.gov/pubmed/22622461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00111.2012
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