Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury

Peroxisome proliferator-activated receptor-α (PPARα) activation attenuates cisplatin (CP)-mediated acute kidney injury by increasing fatty acid oxidation, but mechanisms leading to reduced renal triglyceride (TG) accumulation could also contribute. Here, we investigated the effects of PPARα and CP o...

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Detalhes bibliográficos
Main Authors: Li, Shenyang, Nagothu, Kiran, Ranganathan, Gouri, Ali, Syed M., Shank, Brian, Gokden, Neriman, Ayyadevara, Srinivas, Megyesi, Judit, Olivecrona, Gunilla, Chugh, Sumant S., Kersten, Sander, Portilla, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433869/
https://ncbi.nlm.nih.gov/pubmed/22622461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00111.2012
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