Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

Tumor-associated macrophages (TAMs) are frequently found near pancreatic cancer cells, but it is uncertain whether they are involved in pancreatic cancer progression and the Warburg effect. Here, we show that CCL18 secreted by TAMs facilitates malignant progression and induced a glycolytic phenotype...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ye, Huilin, Zhou, Quanbo, Zheng, Shangyou, Li, Guolin, Lin, Qing, Wei, Lusheng, Fu, Zhiqiang, Zhang, Bin, Liu, Yimin, Li, Zhihua, Chen, Rufu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906621/
https://ncbi.nlm.nih.gov/pubmed/29670110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0486-0
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