Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

Tumor-associated macrophages (TAMs) are frequently found near pancreatic cancer cells, but it is uncertain whether they are involved in pancreatic cancer progression and the Warburg effect. Here, we show that CCL18 secreted by TAMs facilitates malignant progression and induced a glycolytic phenotype...

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Опубликовано в: :Cell Death Dis
Главные авторы: Ye, Huilin, Zhou, Quanbo, Zheng, Shangyou, Li, Guolin, Lin, Qing, Wei, Lusheng, Fu, Zhiqiang, Zhang, Bin, Liu, Yimin, Li, Zhihua, Chen, Rufu
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906621/
https://ncbi.nlm.nih.gov/pubmed/29670110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0486-0
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