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A computational model to predict the Diels–Alder reactivity of aryl/alkyl-substituted tetrazines
ABSTRACT: The tetrazine ligation is one of the fastest bioorthogonal ligations and plays a pivotal role in time-critical in vitro and in vivo applications. However, prediction of the reactivity of tetrazines in inverse electron demand Diels–Alder-initiated ligation reactions is not straight-forward....
Guardat en:
| Publicat a: | Monatsh Chem |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Vienna
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5906496/ https://ncbi.nlm.nih.gov/pubmed/29681659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-017-2110-x |
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