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Small molecule alteration of RNA sequence in cells and animals

RNA regulation and maintenance are critical for proper cell function. Small molecules that specifically alter RNA sequence would be exceptionally useful as probes of RNA structure and function or as potential therapeutics. Here, we demonstrate a photochemical approach for altering the trinucleotide...

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Detalles Bibliográficos
Publicado en:Bioorg Med Chem Lett
Main Authors: Guan, Lirui, Luo, Yiling, Ja, William W., Disney, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906209/
https://ncbi.nlm.nih.gov/pubmed/29079470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.10.034
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