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In vivo neurochemical profile of selectively bred high-responder and low-responder rats reveals baseline, cocaine- and novelty-evoked differences in monoaminergic systems

Relative to bred low-responder (bLR) rats, bred high-responder (bHR) rats have an exaggerated locomotor response to a novel environment, are more risk-taking, more impulsive, and more likely to exhibit compulsive drug-seeking behaviors. These phenotypic differences in addiction-related behaviors and...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Neurosci
Hauptverfasser: Mabrouk, Omar S., Han, John L., Wong, Jenny-Marie T., Akil, Huda, Kennedy, Robert T., Flagel, Shelly B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906149/
https://ncbi.nlm.nih.gov/pubmed/29161023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00294
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