Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

BACKGROUND: Gender and enhanced novelty reactivity can predispose certain individuals to drug abuse. Previous research in male and female rats selectively bred for high or low locomotor reactivity to novelty found that bred High Responders (bHRs) acquire cocaine self-administration more rapidly than...

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Detalhes bibliográficos
Main Authors: Cummings, Jennifer A, Gowl, Brooke A, Westenbroek, Christel, Clinton, Sarah M, Akil, Huda, Becker, Jill B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071306/
https://ncbi.nlm.nih.gov/pubmed/21396095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-6410-2-3
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