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Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats

RATIONALE: Environmental challenges during adolescence, such as drug exposure, can cause enduring behavioral and molecular changes that contribute to life-long maladaptive behaviors, including addiction. Selectively bred high-responder (bHR) and low-responder (bLR) rats represent a unique model for...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: García-Fuster, M. Julia, Parsegian, Aram, Watson, Stanley J., Akil, Huda, Flagel, Shelly B.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792824/
https://ncbi.nlm.nih.gov/pubmed/28210781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4566-0
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