Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic Hepatitis

Alcoholic hepatitis (AH) continues to be a disease with high mortality and no efficacious medical treatment. Although severe AH is presented as acute on chronic liver failure, what underlies this transition from chronic alcoholic steatohepatitis (ASH) to AH, is largely unknown. To address this quest...

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Veröffentlicht in:Hepatology
Hauptverfasser: Khanova, Elena, Wu, Raymond, Wang, Wen, Yan, Rui, Chen, Yibu, French, Samuel W., Llorente, Cristina, Pan, Stephanie Q., Yang, Qihong, Li, Yuchang, Lazaro, Raul, Ansong, Charles, Smith, Richard D., Bataller, Ramon, Morgan, Timothy, Schnabl, Bernd, Tsukamoto, Hidekazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906140/
https://ncbi.nlm.nih.gov/pubmed/29108122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29645
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