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αA-crystallin-derived minichaperone stabilizes αAG98R-crystallin by affecting its zeta potential

PURPOSE: The G98R mutant of αA-crystallin is associated with the development of presenile cataracts. In vitro, the recombinant mutant protein exhibits altered structural and functional characteristics, along with the propensity to aggregate by itself and precipitate. Previously, we have reported tha...

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Pubblicato in:Mol Vis
Autori principali: Phadte, Ashutosh S., Santhoshkumar, Puttur, Sharma, K. Krishna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906106/
https://ncbi.nlm.nih.gov/pubmed/29706763
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