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Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways
A macromolecular complex of the enzymes involved in human de novo purine biosynthesis, the purinosome, has been shown to consist of a core assembly to regulate the metabolic activity of the pathway. However, it remains elusive whether the core assembly itself can be selectively controlled in the cyt...
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| Gepubliceerd in: | PLoS One |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5905998/ https://ncbi.nlm.nih.gov/pubmed/29668719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195989 |
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