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Reduction in Valproic Acid–Induced Neural Tube Defects by Maternal Immune Stimulation: Role of Apoptosis

Teratogenic deregulation of apoptosis during development is a possible mechanism for birth defects. Administration of valproic acid (VA) during first trimester of pregnancy causes neural tube defects (NTDs). Nonspecific stimulation of the mother’s immune system has been shown to reduce various terat...

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Библиографические подробности
Опубликовано в: :Birth Defects Res B Dev Reprod Toxicol
Главные авторы: Mallela, Mural, Hrubec, Theresa
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905423/
https://ncbi.nlm.nih.gov/pubmed/22767483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21018
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