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Reduction in Valproic Acid–Induced Neural Tube Defects by Maternal Immune Stimulation: Role of Apoptosis

Teratogenic deregulation of apoptosis during development is a possible mechanism for birth defects. Administration of valproic acid (VA) during first trimester of pregnancy causes neural tube defects (NTDs). Nonspecific stimulation of the mother’s immune system has been shown to reduce various terat...

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Detalhes bibliográficos
Publicado no:Birth Defects Res B Dev Reprod Toxicol
Main Authors: Mallela, Mural, Hrubec, Theresa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905423/
https://ncbi.nlm.nih.gov/pubmed/22767483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21018
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