Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene

BACKGROUND: Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to chemotherapy, presents several limits such as cancer recurrence and drug resistance. Targeted therapies have more efficacy and less toxi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Mendes Oliveira, Duarte, Grillone, Katia, Mignogna, Chiara, De Falco, Valentina, Laudanna, Carmelo, Biamonte, Flavia, Locane, Rosa, Corcione, Francesco, Fabozzi, Massimiliano, Sacco, Rosario, Viglietto, Giuseppe, Malanga, Donatella, Rizzuto, Antonia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905113/
https://ncbi.nlm.nih.gov/pubmed/29665843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0746-y
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker