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Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial
BACKGROUND: The mammalian target of rapamycin (mTOR) inhibitor everolimus is used in the treatment of breast cancer, neuroendocrine tumors, and renal cancer. The approved 10 mg once-daily dose is associated with considerable adverse effects and it has been suggested that these are associated with th...
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| Publié dans: | Clin Pharmacokinet |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5904242/ https://ncbi.nlm.nih.gov/pubmed/28762135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0582-9 |
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