Performance of Methods for Handling Missing Categorical Covariate Data in Population Pharmacokinetic Analyses

In population pharmacokinetic analyses, missing categorical data are often encountered. We evaluated several methods of performing covariate analyses with partially missing categorical covariate data. Missing data methods consisted of discarding data (DROP), additional effect parameter for the group...

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Bibliografische gegevens
Hoofdauteurs: Keizer, Ron J., Zandvliet, Anthe S., Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385822/
https://ncbi.nlm.nih.gov/pubmed/22648902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9373-2
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