Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism

BACKGROUND & AIMS: Alcohol-induced progression of hepatitis C virus (HCV) infection is related to dysfunction of innate immunity in hepatocytes. Endogenously produced interferon (IFN)α induces activation of interferon-stimulated genes (ISGs) via triggering of the Janus kinase–signal transducer a...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Ganesan, Murali, Tikhanovich, Irina, Vangimalla, Shiva Shankar, Dagur, Raghubendra Singh, Wang, Weimin, Poluektova, Larisa I., Sun, Yimin, Mercer, David F., Tuma, Dean, Weinman, Steven A., Kharbanda, Kusum K., Osna, Natalia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904050/
https://ncbi.nlm.nih.gov/pubmed/29693039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.10.004
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