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Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story

Jumonji domain-containing protein 6 (JMJD6) is a non-heme Fe(II) 2-oxoglutarate (2OG)-dependent oxygenase with arginine demethylase and lysyl hydroxylase activities. Its initial discovery as a dispensable phosphatidylserine receptor (PSR) in the cell membrane of macrophages for phagocytosis was squa...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Vangimalla, Shiva Shankar, Ganesan, Murali, Kharbanda, Kusum K., Osna, Natalia A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485730/
https://ncbi.nlm.nih.gov/pubmed/28587176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7020041
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