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Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β
BACKGROUND & AIMS: The organic solute transporter α-β (OSTα-OSTβ) mainly facilitates transport of bile acids across the basolateral membrane of ileal enterocytes. Therefore, inhibition of OSTα-OSTβ might have similar beneficial metabolic effects as intestine-specific agonists of the major nuclea...
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| Pubblicato in: | Cell Mol Gastroenterol Hepatol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5904037/ https://ncbi.nlm.nih.gov/pubmed/29675448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.11.011 |
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