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Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

Bile salts play a pivotal role in lipid homeostasis, are sensed by specialized receptors, and have been implicated in various disorders affecting the gut or liver. They may play a role either as culprit or as potential panacea. Four very efficient transporters mediate most of the hepatic and intesti...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Kunst, Roni F., Verkade, Henkjan J., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252069/
https://ncbi.nlm.nih.gov/pubmed/33222321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31651
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