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Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation

The bile salt export pump, encoded by ABCB11, is the predominant canalicular transport protein for biliary bile acid secretion. The level of ABCB11 expression in humans is widely variable yet the impact of this variability on human disease is not well defined. We aim to determine the effect of hepat...

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Detalhes bibliográficos
Main Authors: Henkel, Anne S., Gooijert, Karin E. R., Havinga, Rick, Boverhof, Renze, Green, Richard M., Verkade, Henkjan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543647/
https://ncbi.nlm.nih.gov/pubmed/23139217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00322.2012
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