Developmental Social Communication Deficits in the Shank3 Rat Model of Phelan-McDermid Syndrome and Autism Spectrum Disorder

Mutations in the SHANK3 gene have been discovered in autism spectrum disorders (ASD), and the intellectual disability, Phelan-McDermid Syndrome (PMS). This study leveraged a new rat model of Shank3 deficiency to assess complex behavioral phenomena, unique to rats, which display a richer social behav...

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Detalhes bibliográficos
Publicado no:Autism Res
Main Authors: Berg, Elizabeth L, Copping, Nycole A, Rivera, Josef K, Pride, Michael C, Careaga, Milo, Bauman, Melissa D, Berman, Robert F, Lein, Pamela J, Harony-Nicholas, Hala, Buxbaum, Joseph D, Ellegood, Jacob, Lerch, Jason P, Wöhr, Markus, Silverman, Jill L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903935/
https://ncbi.nlm.nih.gov/pubmed/29377611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/aur.1925
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