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Behavioral Phenotyping of an Improved Mouse Model of Phelan–McDermid Syndrome with a Complete Deletion of the Shank3 Gene

Phelan–McDermid syndrome (PMS) is a rare genetic disorder in which one copy of the SHANK3 gene is missing or mutated, leading to a global developmental delay, intellectual disability (ID), and autism. Multiple intragenic promoters and alternatively spliced exons are responsible for the formation of...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Drapeau, Elodie, Riad, Mohammed, Kajiwara, Yuji, Buxbaum, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175061/
https://ncbi.nlm.nih.gov/pubmed/30302388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0046-18.2018
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