A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and presence of cancer cells with properties of normal tissue stem cells(1,2). Secreted Wnt signals maintain stem cells in various epithelial tissues, including in lung development and regeneration(...

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Publicado en:Nature
Main Authors: Tammela, Tuomas, Sanchez-Rivera, Francisco J., Cetinbas, Naniye Malli, Wu, Katherine, Joshi, Nikhil S., Helenius, Katja, Park, Yoona, Azimi, Roxana, Kerper, Natanya R., Wesselhoeft, R. Alexander, Gu, Xin, Schmidt, Leah, Cornwall-Brady, Milton, Yilmaz, Ömer H., Xue, Wen, Katajisto, Pekka, Bhutkar, Arjun, Jacks, Tyler
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903678/
https://ncbi.nlm.nih.gov/pubmed/28489818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22334
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