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Tolerogenic Ag-PLG Nanoparticles Induce Tregs to Suppress Activated Diabetogenic CD4 and CD8 T Cells
Type 1 diabetes (T1D) is mediated by destruction of pancreatic β cells by autoantigen-specific CD4(+) and CD8(+) T cells, thus the ideal solution for T1D is the restoration of immune tolerance to β cell antigens. We demonstrate the ability of carboxylated 500nm biodegradable poly(lactide-co-glycolid...
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| Publicado no: | J Autoimmun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5902637/ https://ncbi.nlm.nih.gov/pubmed/29258717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2017.12.010 |
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