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Heritable, Allele-Specific Chromosomal Looping between Tandem Promoters Specifies Promoter Usage of SHC1

One-half of the genes in the human genome contain alternative promoters, some of which generate products with opposing functions. Aberrant silencing or activation of such alternative promoters is associated with multiple diseases, including cancer, but little is known regarding the molecular mechani...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Li, Xichuan, Lin, Zhenzhen, Wang, Hao, Zhao, Dan, Xu, Xing, Wei, Yiliang, Li, Xiaoting, Li, Xiaobo, Xiang, Yougui, Terada, Lance S., Liu, Zhe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902595/
https://ncbi.nlm.nih.gov/pubmed/29440311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00658-17
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