Aiolos Promotes Anchorage Independence by Silencing p66(Shc) Transcription in Cancer Cells

Anchorage of tissue cells to their physical environment is an obligate requirement for survival which is lost in mature hematopoietic and in transformed epithelial cells. Here we find that a lymphocyte lineage-restricted transcription factor, Aiolos, is frequently expressed in lung cancers and predi...

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Autors principals: Li, Xichuan, Xu, Zhao, Du, Wei, Zhang, Zhenfa, Wei, Yiliang, Wang, Hao, Zhu, Zhiyan, Qin, Litao, Wang, Lin, Niu, Qing, Zhao, Xiulan, Girard, Luc, Gong, Yimei, Ma, Zhenyi, Sun, Baocun, Yao, Zhi, Minna, John D., Terada, Lance S., Liu, Zhe
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070880/
https://ncbi.nlm.nih.gov/pubmed/24823637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.03.020
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