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Heritable, Allele-Specific Chromosomal Looping between Tandem Promoters Specifies Promoter Usage of SHC1

One-half of the genes in the human genome contain alternative promoters, some of which generate products with opposing functions. Aberrant silencing or activation of such alternative promoters is associated with multiple diseases, including cancer, but little is known regarding the molecular mechani...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Li, Xichuan, Lin, Zhenzhen, Wang, Hao, Zhao, Dan, Xu, Xing, Wei, Yiliang, Li, Xiaoting, Li, Xiaobo, Xiang, Yougui, Terada, Lance S., Liu, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902595/
https://ncbi.nlm.nih.gov/pubmed/29440311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00658-17
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