The impact of serotype-specific vaccination on phylodynamic parameters of Streptococcus pneumoniae and the pneumococcal pan-genome

In the United States, the introduction of the heptavalent pneumococcal conjugate vaccine (PCV) largely eliminated vaccine serotypes (VT); non-vaccine serotypes (NVT) subsequently increased in carriage and disease. Vaccination also disrupts the composition of the pneumococcal pangenome, which include...

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Udgivet i:PLoS Pathog
Main Authors: Azarian, Taj, Grant, Lindsay R., Arnold, Brian J., Hammitt, Laura L., Reid, Raymond, Santosham, Mathuram, Weatherholtz, Robert, Goklish, Novalene, Thompson, Claudette M., Bentley, Stephen D., O’Brien, Katherine L., Hanage, William P., Lipsitch, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902063/
https://ncbi.nlm.nih.gov/pubmed/29617440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006966
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