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Association of the Pneumococcal Pilus with Certain Capsular Serotypes but Not with Increased Virulence

The recent discovery of a mobile genetic element encoding a pilus-like structure in Streptococcus pneumoniae and the demonstration of a role for the pilus in virulence in mice have led to the proposal of the use of the pilus as a candidate pneumococcal vaccine. We examined the frequency of occurrenc...

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Dettagli Bibliografici
Autori principali: Basset, Alan, Trzcinski, Krzysztof, Hermos, Christina, O'Brien, Katherine L., Reid, Raymond, Santosham, Mathuram, McAdam, Alexander J., Lipsitch, Marc, Malley, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933072/
https://ncbi.nlm.nih.gov/pubmed/17392439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00265-07
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