The impact of serotype-specific vaccination on phylodynamic parameters of Streptococcus pneumoniae and the pneumococcal pan-genome

In the United States, the introduction of the heptavalent pneumococcal conjugate vaccine (PCV) largely eliminated vaccine serotypes (VT); non-vaccine serotypes (NVT) subsequently increased in carriage and disease. Vaccination also disrupts the composition of the pneumococcal pangenome, which include...

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Publicado en:PLoS Pathog
Autores principales: Azarian, Taj, Grant, Lindsay R., Arnold, Brian J., Hammitt, Laura L., Reid, Raymond, Santosham, Mathuram, Weatherholtz, Robert, Goklish, Novalene, Thompson, Claudette M., Bentley, Stephen D., O’Brien, Katherine L., Hanage, William P., Lipsitch, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902063/
https://ncbi.nlm.nih.gov/pubmed/29617440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006966
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