Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a

PURPOSE: We previously reported using statins was correlated with improved metastasis free survival in aggressive breast cancer. The purpose of this study was to examine the effect of statins on metastatic colonization by triple negative breast cancer (TNBC) cells. EXPERIMENTAL DESIGN: TNBC cell lin...

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Publicat a:Breast Cancer Res Treat
Autors principals: Wolfe, Adam R., Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Bambhroliya, Arvind, Huang, Xuelin, Bertucci, Francois, Finetti, Pascal, Birnbaum, Daniel, Van Laere, Steven, Diagaradjan, Parmeswaran, Ruffell, Brian, Trenton, Nicholaus J., Chu, Khoi, Hittelman, Walter, Diehl, Michael, Levental, Ilya, Ueno, Naoto T., Woodward, Wendy A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901982/
https://ncbi.nlm.nih.gov/pubmed/26590814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3645-3
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