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Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a

PURPOSE: We previously reported using statins was correlated with improved metastasis free survival in aggressive breast cancer. The purpose of this study was to examine the effect of statins on metastatic colonization by triple negative breast cancer (TNBC) cells. EXPERIMENTAL DESIGN: TNBC cell lin...

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書誌詳細
出版年:Breast Cancer Res Treat
主要な著者: Wolfe, Adam R., Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Bambhroliya, Arvind, Huang, Xuelin, Bertucci, Francois, Finetti, Pascal, Birnbaum, Daniel, Van Laere, Steven, Diagaradjan, Parmeswaran, Ruffell, Brian, Trenton, Nicholaus J., Chu, Khoi, Hittelman, Walter, Diehl, Michael, Levental, Ilya, Ueno, Naoto T., Woodward, Wendy A.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901982/
https://ncbi.nlm.nih.gov/pubmed/26590814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3645-3
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