Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a

PURPOSE: We previously reported using statins was correlated with improved metastasis free survival in aggressive breast cancer. The purpose of this study was to examine the effect of statins on metastatic colonization by triple negative breast cancer (TNBC) cells. EXPERIMENTAL DESIGN: TNBC cell lin...

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Udgivet i:Breast Cancer Res Treat
Main Authors: Wolfe, Adam R., Debeb, Bisrat G., Lacerda, Lara, Larson, Richard, Bambhroliya, Arvind, Huang, Xuelin, Bertucci, Francois, Finetti, Pascal, Birnbaum, Daniel, Van Laere, Steven, Diagaradjan, Parmeswaran, Ruffell, Brian, Trenton, Nicholaus J., Chu, Khoi, Hittelman, Walter, Diehl, Michael, Levental, Ilya, Ueno, Naoto T., Woodward, Wendy A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901982/
https://ncbi.nlm.nih.gov/pubmed/26590814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3645-3
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