Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study

BACKGROUND: Plasma renin is an important regulator of blood pressure (BP). Plasma renin activity (PRA) has been shown to correlate with variability in BP response to antihypertensive agents. We conducted a genome-wide association study to identify SNPs associated with baseline PRA using data from th...

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Publicado no:Circ Genom Precis Med
Main Authors: McDonough, Caitrin W., Magvanjav, Oyunbileg, Sá, Ana C.C., El Rouby, Nihal M., Dave, Chintan, Deitchman, Amelia N., Kawaguchi-Suzuki, Marina, Mei, Wenbin, Shen, Yong, Singh, Ravi Shankar Prasad, Solayman, Mohamed, Bailey, Kent R., Boerwinkle, Eric, Chapman, Arlene B., Gums, John G., Webb, Amy, Scherer, Steven E., Sadee, Wolfgang, Turner, Stephen T., Cooper-DeHoff, Rhonda M., Gong, Yan, Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901893/
https://ncbi.nlm.nih.gov/pubmed/29650764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.001854
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