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Differential Effects of Overexpression of Rab5 and Rab22 on Autophagy in PC12 Cells with or without NGF

Macroautophagy selectively recycles damaged or unneeded proteins and organelles by degradation via targeting to the autophagosome. The following method seeks to identify candidate Rab GTPases that likely modulate autophagy in PC12 cells during nerve growth factor (NGF) starvation. This microscopy-ba...

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Pubblicato in:Methods Mol Biol
Autori principali: Marlin, M. Caleb, Li, Guangpu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901729/
https://ncbi.nlm.nih.gov/pubmed/25800852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2569-8_25
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