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Rab22 controls NGF signaling and neurite outgrowth in PC12 cells
Rab22 is a small GTPase that is localized on early endosomes and regulates early endosomal sorting. This study reports that Rab22 promotes nerve growth factor (NGF) signaling-dependent neurite outgrowth and gene expression in PC12 cells by sorting NGF and the activated/phosphorylated receptor (pTrkA...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192864/ https://ncbi.nlm.nih.gov/pubmed/21849477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0277 |
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