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Rab22 controls NGF signaling and neurite outgrowth in PC12 cells

Rab22 is a small GTPase that is localized on early endosomes and regulates early endosomal sorting. This study reports that Rab22 promotes nerve growth factor (NGF) signaling-dependent neurite outgrowth and gene expression in PC12 cells by sorting NGF and the activated/phosphorylated receptor (pTrkA...

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Autori principali: Wang, Liang, Liang, Zhimin, Li, Guangpu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192864/
https://ncbi.nlm.nih.gov/pubmed/21849477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0277
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