SPLUNC1 is an allosteric modulator of the epithelial sodium channel

Cystic fibrosis (CF) is a common genetic disease with significantly increased mortality. CF airways exhibit ion transport abnormalities, including hyperactivity of the epithelial Na(+) channel (ENaC). Short-palate lung and nasal epithelial clone 1 (SPLUNC1) is a multifunctional innate defense protei...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Kim, Christine Seulki, Ahmad, Saira, Wu, Tongde, Walton, William G., Redinbo, Matthew R., Tarran, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901381/
https://ncbi.nlm.nih.gov/pubmed/29295861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701126R
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