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Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1
SPLUNC1 is an abundantly secreted innate immune protein in the mammalian respiratory tract that exerts bacteriostatic and antibiofilm effects, binds to lipopolysaccharide (LPS), and acts as a fluid-spreading surfactant. Here, we unravel the structural elements essential for the surfactant and antimi...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887393/ https://ncbi.nlm.nih.gov/pubmed/27145151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00271 |
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