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The Physiology of Obese-Hyperglycemic Mice [ob/ob Mice]

This review summarizes key aspects of what has been learned about the physiology of leptin deficiency as it can be observed in obese-hyperglycemic ob/ob mice. These mice lack functional leptin. They are grossly overweight and hyperphagic, particularly at young ages, and develop severe insulin resist...

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Bibliografski detalji
Izdano u:ScientificWorldJournal
Glavni autor: Lindström, Per
Format: Artigo
Jezik:Inglês
Izdano: TheScientificWorldJOURNAL 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901356/
https://ncbi.nlm.nih.gov/pubmed/17619751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2007.117
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