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The Physiology of Obese-Hyperglycemic Mice [ob/ob Mice]
This review summarizes key aspects of what has been learned about the physiology of leptin deficiency as it can be observed in obese-hyperglycemic ob/ob mice. These mice lack functional leptin. They are grossly overweight and hyperphagic, particularly at young ages, and develop severe insulin resist...
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Publicado no: | ScientificWorldJournal |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
TheScientificWorldJOURNAL
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901356/ https://ncbi.nlm.nih.gov/pubmed/17619751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2007.117 |
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