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Survivin is a novel transcription regulator of KIT and is downregulated by miRNA‐494 in gastrointestinal stromal tumors

Gain‐of‐function mutations of KIT are pathognomonic in sporadic gastrointestinal stromal tumors (GISTs). Several microRNAs have been shown to be dysregulated in GISTs and impact KIT expression. Little is known though on KIT‐independent targets of KIT‐regulating mRNAs. We sought to investigate how mi...

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Bibliografski detalji
Izdano u:Int J Cancer
Glavni autori: Yun, SeongJu, Kim, Won Kyu, Kwon, Yujin, Jang, Mi, Bauer, Sebastian, Kim, Hoguen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900938/
https://ncbi.nlm.nih.gov/pubmed/29277888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31235
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