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Survivin is a novel transcription regulator of KIT and is downregulated by miRNA‐494 in gastrointestinal stromal tumors

Gain‐of‐function mutations of KIT are pathognomonic in sporadic gastrointestinal stromal tumors (GISTs). Several microRNAs have been shown to be dysregulated in GISTs and impact KIT expression. Little is known though on KIT‐independent targets of KIT‐regulating mRNAs. We sought to investigate how mi...

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Dades bibliogràfiques
Publicat a:Int J Cancer
Autors principals: Yun, SeongJu, Kim, Won Kyu, Kwon, Yujin, Jang, Mi, Bauer, Sebastian, Kim, Hoguen
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900938/
https://ncbi.nlm.nih.gov/pubmed/29277888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31235
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