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E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases

RAS proteins are major human oncogenes, and most of the studies are focused on enzymatic RAS effectors. Recently, nonenzymatic RAS effectors (RASSF, RAS association domain family) have garnered special attention because of their tumor-suppressive properties in contrast to the oncogenic potential of...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Karthik, Isai Pratha, Desai, Pavitra, Sukumar, Sudarkodi, Dimitrijevic, Aleksandra, Rajalingam, Krishnaraj, Mahalingam, Sundarasamy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900760/
https://ncbi.nlm.nih.gov/pubmed/29467226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000623
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