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E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases

RAS proteins are major human oncogenes, and most of the studies are focused on enzymatic RAS effectors. Recently, nonenzymatic RAS effectors (RASSF, RAS association domain family) have garnered special attention because of their tumor-suppressive properties in contrast to the oncogenic potential of...

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Pubblicato in:J Biol Chem
Autori principali: Karthik, Isai Pratha, Desai, Pavitra, Sukumar, Sudarkodi, Dimitrijevic, Aleksandra, Rajalingam, Krishnaraj, Mahalingam, Sundarasamy
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900760/
https://ncbi.nlm.nih.gov/pubmed/29467226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000623
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