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Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers

With predictions showing that 131.5 million people worldwide will be living with dementia by 2050, an understanding of the molecular mechanisms underpinning disease is crucial in the hunt for novel therapeutics and for biomarkers to detect disease early and/or monitor disease progression. The metabo...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Quinn, James P., Corbett, Nicola J., Kellett, Katherine A. B., Hooper, Nigel M.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900574/
https://ncbi.nlm.nih.gov/pubmed/29630551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170959
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