Autoimmune Lymphoproliferative Syndrome-FAS Patients Have an Abnormal Regulatory T Cell (Treg) Phenotype but Display Normal Natural Treg-Suppressive Function on T Cell Proliferation

OBJECTIVE: Autoimmune lymphoproliferative syndrome (ALPS) with FAS mutation (ALPS-FAS) is a nonmalignant, noninfectious, lymphoproliferative disease with autoimmunity. Given the central role of natural regulatory T cells (nTregs) in the control of lymphoproliferation and autoimmunity, we assessed nT...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Mazerolles, Fabienne, Stolzenberg, Marie-Claude, Pelle, Olivier, Picard, Capucine, Neven, Benedicte, Fischer, Alain, Magerus-Chatinet, Aude, Rieux-Laucat, Frederic
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900038/
https://ncbi.nlm.nih.gov/pubmed/29686686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00718
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki